BL19U2: Small-angle X-ray scattering beamline for biological macromolecules in solution at SSRF

• 作者: Chun-Xia Hong Feng-Gang Bian Guang-Feng Liu Hong-Jin Wu Na Li Ping Zhou Yi-Wen Li
• 来源期刊: 核技术（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: SYNCHROTRON RADIATION TECHNOLOGY AND APPLICATIONS
• 页码范围: 32-40
• 页数: 9页
• 语种: 英文

摘要

The BL19U2 at the Shanghai Synchrotron Radiation Facility is a small-angle X-ray scattering beamline dedicated to structural studies pertaining to bio-logical macromolecules in solution. The beamline has been officially opened to users in March 2015, and since then, a series of technological innovations has been developed to optimize beamline performance, thereby significantly improving the data collection efficiency and broadening the application scope of biological small-angle X-ray scatter-ing. BL19U2 is ideal for the high-throughput screening of weakly scattered proteins, protein assemblies, nucleic acids, inorganic nanomaterials, and organic drug mole-cules. This paper describes the design and overview of the BL19U2 beamline. Versatile sample environments at the experimental station and some recent scientific highlights are presented.