Ever since its discovery on April 8, 1911, superconductivity has been a defining hallmark for condensed matter physics and a driving force for new physics and technology.For the past century,condensed matter physicists have devoted to searching for novel superconductors, raising their critical temperatures (To), and deciphering their mysterious mechanisms.Two prime examples are the celebrated high-temperature cuprate superconductors and the amazing magic-angle graphene superconductor.Since about a decade ago, tremendous efforts have been made to create topological superconductivity (TSC) that supports fractionalized quasiparticles (compared with the Cooper pairs of charge 2e) [1],inspired by the far-reaching success in realizing topological insulators.Now, writing in Nature Physics, a research team led by Jian Wang at Peking University reports an experimental breakthrough [2] that ingeniously utilize an atomic line defect in a 2D high-temperature superconductor to materialize the long desired yet elusive 1D time-reversal-invariant TSC that hosts Majorana Kramers pairs [3].