Resident macrophages keep mitochondria running in the heart

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: RESEARCH HIGHLIGHTS
• 页码范围: 1057-1058
• 页数: 2页
• 语种: 英文

摘要

The high workload of cardiac myocytes,coupled with their negligible turnover,requires that compensatory mechanisms act in the heart to address ongoing cellular damage and extruded organelle components that would otherwise accu?mulate.A recent study in Cell by Nicolás-ávila et al.illustrates how cardiac-resident macrophages serve such a role,by clearing extruded mitochondrial debris to preserve organ homeostasis and maintain optimal cardiac function.