Molecular Characterization of HIV-1-circulating Strains among Pre-Treatment Patients in Tibet

• 作者: Baimayangjin DONG Ao Bo Dorjiwangmo FENG Yi GAN Meng Ze LIAO Ling Jie LIU Lei RUAN Yu Hua SHAO Yi Ming Tashibazong XING Hui
• 来源期刊: 生物医学与环境科学（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 953-958,中插7
• 页数: 7页
• 语种: 英文
• DOI: 10.3967/bes2020.132

摘要

The Tibet Autonomous Region (referred to as'Tibet') is located in southwestern China, bordering the Yunnan Province, Sichuan Province, Xinjiang Uygur Autonomous Region, and other provinces with high HIV/AIDS prevalence, as well as India, Nepal, and other high-risk border countries. In 1994, the first patient with HIV-1 infection was detected at Zhangmu port, Namu County, Shigatse, Tibet. In 2005, the first AIDS cases were reported among local Tibetans. A total of 253 cases of HIV/AIDS were reported between 2004 and 2013. The number of HIV/AIDS cases in Tibet is increasing each year, and this epidemic encompasses seven cities throughout the region. Even though the overall epidemic has a low countrywide prevalence, the prevention and control of HIV-1 in Tibet cannot be ignored. Previous studies on patients with HIV-1 in Tibet have mainly focused on epidemiological studies, and to the best of our knowledge, no relevant study has reported the genotype of HIV-1. Therefore, this study aimed to analyze the genotype and source of HIV-1 infection strains in Tibet.