ABAting the Response: A Novel ABA Signal Terminator that Disrupts the Hormone Co-receptor Complex

• 作者: Akhtar Ali Dae-Jin Yun Jose M.Pardo
• 来源期刊: 分子植物（英文版）
• 年，卷（期）: 2020,（9）
• 所属期刊栏目: Spotlights
• 页码范围: 1241-1243
• 页数: 3页
• 语种: 英文

摘要

The phytohormone abscisic acid (ABA) regulates multiple physiological processes such as embryo morphogenesis, seed maturation and germination, leaf senescence, fruit ripening, and stress adaptation(Gupta et al., 2020).ABA levels quickly rise in response to conditions leading to water deficit, including the developmental processes of seed drying and dormancy, as well as early post-germinative growth (Chen et al., 2020).Several proteins, commonly regarded as the ABA signaling core components, have been identified.Among them are the ABA receptors (PYR/PYL/RCAR), type 2C Ser/Thr protein phosphatases (PP2Cs), which act as ABA co-receptors, SNF1-related protein kinases (SnRK2S), and transcription factors (ABI5/ABFS) that govern ABA-responsive gene expression (Chen et al., 2020).Upon ABA binding, the receptors PYR/PYL/RCAR create an interaction surface that recruits and inhibits PP2C phosphatases, thereby allowing the activation of SnRK2 kinases that subsequently phosphorylate downstream components.The operation of the core signaling intermediaries produces a forward relay of encoded information that elicits diverse outputs.Bifurcations of this central and lineal pathway lead to other physiological events, e.g., the activation or inhibition of ion transporters underpinning stomatal movements (Chen et al., 2020).