Efficient Pd-Catalyzed C-H Oxidative Bromination of Arenes with Dimethyl Sulfoxide and Hydrobromic Acid

• 作者: Yizhi Yuan Yujie Liang Shihui Shi Yu-Feng Liang Ning Jiao
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2020,（11）
• 所属期刊栏目: Concise Reports
• 页码范围: 1245-1251
• 页数: 7页
• 语种: 英文
• DOI: 10.1002/cjoc.202000055

摘要

We have developed an efficient Pd-catalyzed directed C-H bromination protocol,in which dimethyl sulfoxide(DMSO)is employed as oxidant with hydrobromic acid aqueous solution(HBr(aq))as bromide source.The DMSO/HBr(aq)system,which is novelly and eficiently utilized in transition-metal catalyzed C-H activation,illustrates its practicability by the operational simplicity,inexpensive and readily available starting materials,and high bromide-atom economy.