This special issue focuses on the emerging technology of addi-tive manufacturing,also known as three-dimensional(3D)print-ing.This topic is derived from a keynote lecture presented at the 2019 International Summit Forum on Engineering Science and Technology Strategy:From Frontier Technology to Research and Development of Products Using Medical Additive Manufacturing.The Summit Forum was organized by the Chinese Academy of Engineering(CAE)and took place in mid-June 2019 in Shenzhen,China.The topics covered by this special issue include the research and development of raw materials,design and 3D manufacturing technologies,and the preclinical testing and clinical applications of additive manufacturing in orthopedics and related fields.The authors of the articles published in this issue are leading experts from academia,hospitals,industry,and regulatory bodies,and include fellows and academicians from the academies of science and of engineering of Canada,China,France,and the United States.