Design and Application of Indole-Based Allylic Donors for Pd-Catalyzed Decarboxylative Allylation Reactions

• 作者: Qing-Qing Hang Si-Jia Liu Lei Yu Ting-Ting Sun Yu-Chen Zhang Guang-Jian Mei Feng Shi
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2020,（12）
• 所属期刊栏目: Concise Reports
• 页码范围: 1612-1618
• 页数: 7页
• 语种: 英文
• DOI: 10.1002/cjoc.202000104

摘要

A new class of indole-bbased allylic donors have been designed and developed for palladium-catalyzed decarboxylative allylations.In addition,the first application of these indole-based allylic donors in palladium-catalyzed decarboxylative[3+2]cycloaddi-tion and allylic amination has been achieved by reacting with isocyanates and sulfonyl amines,respectively.This approach represents the first design of indole-based allylic donors,which is helpful for settling the challenge of designing and developing new class of heterocycle-based allylic donors for Pd-catalyzed decarboxylative allylation reactions.Moreover,the application of this new class of allylic donors in cycloadditions and substitutions will add new contents to the research field of decarboxylative allylation.