Effects of primary glaucoma on sleep quality and daytime sleepiness of patients residing at an equatorial latitude

• 作者: Augustinus Laude Boon Ang Lim Chun Hau Chua Elizabeth YW Poh Hannah TY Wang Hon Tym Wong Jacob YH Chin Leonard WL Yip Owen Kim Hee Vernon KY Yong Ying Tai Lo Zhi Hong Toh
• 来源期刊: 国际眼科杂志:英文版
• 学科: 医学
• 关键词: sleep disturbances primary glaucoma intrinsically photosensitive retinal ganglion cells daytime sleepiness sleep quality South-East Asia
• 年，卷（期）: 2020,（9）
• 页码范围: 1451-1458
• 页数: 8页
• 分类号: R775.2

摘要

AIM:To investigate the impact of primary glaucoma on sleep quality and daytime sleepiness of patients.METHODS:Prospective cross-sectional study with consecutive sampling in South-East Asian population was performed.Validated questionnaires:the Pittsburg Sleep Quality Index(PSQI)and Epworth Sleepiness Scale(ESS)were administered prospectively.Subjects with nonglaucomatous optic neuropathy or concomitant retinal pathology were excluded.Glaucoma severity was based on HVF 24-2 perimetry.Binocular single vision was represented based on the better eye.Frequency of and predictive factors for poor sleep quality and excessive daytime sleepiness were compared.RESULTS:A total of 79 primary open angle glaucoma(POAG),27 primary angle-closure glaucoma(PACG)patients,and 89 controls were recruited.PACG patients had higher median PSQI scores(P=0.004)and poorer sleep quality(P<0.001).Compared to controls,PACG patients were 3.34 times more likely to have poor sleep quality(P=0.008),which remained significant after adjustment for demographics(P=0.016)and predictive variables(P=0.013).PACG patients have poorer sleep quality when visual acuity(VA)was 6/15 or worse(P=0.009).Univariate and multivariate analysis of predictive variables for poor sleep quality and daytime sleepiness did not find statistical significance.CONCLUSION:PACG patients have poorer sleep quality but not daytime sleepiness.This is important in South-East Asian population with heavy disease burden.Evaluations on sleep disturbances can be considered to provide more ho istic care.