Metabolomic modulations in a freshwater microbial community exposed to the fungicide azoxystrobin

• 作者: Haifeng Qian Mengwei Zhang Mingjing Ke Qian Qu Tao Lu Wanyue Liu Zhenyan Zhang Zhigao Zhou
• 来源期刊: 环境科学学报（英文版）
• 年，卷（期）: 2020,（11）
• 页码范围: 102-109
• 页数: 8页
• 语种: 英文

摘要

An effective broad-spectrum fungicide,azoxystrobin (AZ),has been widely detected in aquatic ecosystems,potentially affecting the growth of aquatic microorganisms.In the present study,the eukaryotic alga Monoraphidlium sp.and the cyanobacterium Pseudanabaena sp.were exposed to AZ for 7 days.Our results showed that 0.2-0.5 mg/L concentrations of AZ slightly inhibited the growth of Monoraphidium sp.but stimulated Pseudanabaena sp.growth.Meanwhile,AZ treatment effectively increased the secretion of total organic carbon (TOC) in the culture media of the two species,and this phenomenon was also found in a freshwater microcosm experiment (containing the natural microbial community).We attempted to assess the effect of AZ on the function of aquatic microbial communities through metabolomic analysis and further explore the potential risks of this compound.The metabonomic profiles of the microcosm indicated that the most varied metabolites after AZ treatment were related to the citrate cycle (TCA),fatty acid biosynthesis and purine metabolism.We thereby inferred that the microbial community increased extracellular secretions by adjusting metabolic pathways,which might be a stress response to reduce AZ toxicity.Our results provide an important theoretical basis for further study of fungicide stress responses in aquatic microcosm microbial communities,as well as a good start for further explorations of AZ detoxification mechanisms,which will be valuable for the evaluation of AZ environmental risk.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	Mengwei Zhang	中国科学院新疆理化技术研究所	1	0	0.0	0.0
2	Wanyue Liu	中国科学院新疆理化技术研究所	1	0	0.0	0.0
3	Qian Qu	中国科学院新疆理化技术研究所	1	0	0.0	0.0
4	Mingjing Ke	中国科学院新疆理化技术研究所	1	0	0.0	0.0
5	Zhenyan Zhang	中国科学院新疆理化技术研究所	1	0	0.0	0.0
6	Zhigao Zhou	中国科学院新疆理化技术研究所	1	0	0.0	0.0
7	Tao Lu	中国科学院新疆理化技术研究所	1	0	0.0	0.0
8	Haifeng Qian	中国科学院新疆理化技术研究所	1	0	0.0	0.0