Clinical Evidence of Effective Therapy for Prostate Inflammation Based on a Combination of Macrolides and Men’s Pads

• 作者: Edvard V. Kryzhanovskii Alexander B. Yavorsky Lim Kwong Choong
• 来源期刊: 炎症(英文)
• 学科: 医学
• 关键词: PROSTATITIS Men’s Pad Combination Therapy
• 年，卷（期）: yzyw_2021,（1）
• 页码范围: 1-9
• 页数: 9页
• 分类号: R69

摘要

Prostatitis is a widespread disease associated with pelvic pain syndrome, which is characterized by pelvic pain, various urinary symptoms, and possible sexual dysfunction. An adequate therapy requires schemes for chronic prostatitis that affects, among other things, the atypical causative agents. We investigate a therapy for prostate inflammation consisting in a combination of macrolides with the usage of men’s pads for underwear during the treatment. We demonstrate the efficacy of this therapy on a group of patients with chronic prostatitis. The group of patients under this combination therapy exhibits better recovery dynamics compared to the group of patients who were treated only by macrolides. We observe a statistically significant (p-value < 0.01) difference between the two groups in the data from three sections of the NIH-CPSI questionnaire, which concerned pain, symptoms of impaired urination, and quality of life. The number of patients with soreness of the prostate, with the presence of bacteria and leukocytes in the prostate gland secretion, and with the presence of microorganisms in the PCR tests after treatment was lower in the combination therapy group compared to the macrolide group. The obtained results demonstrate that the use of macrolides in combination with the use of men’s pads in the treatment of chronic prostate inflammation, including “abacterial” prostatitis, is promising. More generally, our results highlight the importance of flexible and individual approaches to the treatment of chronic prostatitis.