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摘要:
Objective:To compare the risk of target organ damage in masked hypertension(MH)and sustained hypertension(SH).Methods:A systematic review and meta-analysis was performed.A search of PubMed,Embase,and the Cochrane Library of relevant case-control studies was performed from inception to December 2019,and articles on MH and SH selected according to the inclusion criteria were analyzed.The primary end point was target organ damage in the heart.The secondary end points were target organ damage in the kidneys and blood vessels.Results:Seventeen studies that met the screening criteria were included in the meta-analysis.Compared with the SH group,in the MH group carotid intima-media thickness(IMT)and E/A ratio were signifi cantly greater and the prevalence of left ventricular remodeling and the pulse wave velocity were signifi cantly lower.Other indicators in the heart,kidneys,and blood vessels were not statistically different between the two groups.IMT:P=0.01,E/A ratio:P=0.01,prevalence of left ventricular remodeling:P=0.02,pulse wave velocity:P=0.01.Conclusion:Our study has shown that MH may have almost the same degree of target organ damage as SH,so clinicians may need to consider target organ damage.
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篇名 Risk of Target Organ Damage in Patients with Masked Hypertension versus Sustained Hypertension:A Meta-analysis
来源期刊 Cardiovascular Innovations and Applications 学科 医学
关键词 masked hypertension sustained hypertension target organ META-ANALYSIS
年,卷(期) 2021,(1) 所属期刊栏目
研究方向 页码范围 155-163
页数 9页 分类号 R54
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masked
hypertension
sustained
hypertension
target
organ
META-ANALYSIS
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Cardiovascular Innovations and Applications
季刊
2009-8618
Beijing Anzhen Hospi
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42
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