A review of lignans from genus Kadsura and their spectrum characteristics

• 作者: Liu Zhang Yan-zhe Jia Bin Li Cai-yun Peng Yu-pei Yang Wei Wang Chang-xiao Liu
• 来源期刊: 中草药（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Reviews
• 页码范围: 157-166
• 页数: 10页
• 语种: 英文

摘要

Kadsura belongs to the Schisandroideae subfamily of Magnoliaceae.Plants from genus Kadsura are widely distributed in the South and Southwest of China.The plants of the genus are widely used as folk medicine for a long time in history,with the functions of relieving pain,promoting 'qi'circulation,activating blood resolve stasis,and applications in the treatment of rheumatoid arthritis and gastroenteric disorders.Lignans are the primary characteristic constituents with various biological activities of plants from genus Kadsura.This paper summarized 81 lignans isolated from the plants of genus Kadsura over the past eight years (from 2014 to 2021),which belong to five types:dibenzocyclooctadienes,spirobenzofuranoid dibenzocyclooctadienes,aryltetralins,diarylbutanes and tetrahydrofurans.Each type of these lignans possess typical characteristics in proton magnetic resonance (1H NMR) and carbon-13 nuclear magnetic resonance (13C NMR) spectra,the NMR regularities of these types of lingans were summarized,which provided a useful reference for the structural analysis of lignans.The relationships between lignans and pharmacodynamics were also systematically analyzed,lignans were predicted to be the quality markers (Q-marker) of Kadsura genus.