Chemical Composition and Biological Significance of Thymol as Antiparasitic

• 作者: Wafaa M. Hikal Kirill G. Tkachenko Hussein A. H. Said-Al Ahl Hoda Sany Ali S. Sabra Rowida S. Baeshen Amra Bratovcic
• 来源期刊: 生态学期刊(英文)
• 学科: 医学
• 关键词: THYMOL Chemical Composition Biological Activity ANTIPARASITIC
• 年，卷（期）: 2021,（3）
• 页码范围: 240-266
• 页数: 27页
• 分类号: R53

摘要

Thymol is one of the most important phytochemical components because of its pharmacological and bioactive potential effects. This review focuses particularly on thymol as an alternative natural antiparasitic with potential use in the pharmaceutical industry. This is in line with the preferences of the natural products for treatment being safer and without side effects. The biosynthesis pathways of thymol and carvacrol have been discussed, and mechanism of action of thymol on parasites. Studies on thymol confirmed the activity of thymol as anti-parasite against anthelmintic, <em>Trypanosoma</em> ssp., <em>Toxoplasma gondii</em>, <em>Leishmania</em> spp., <em>Plasmodium falciparum</em>, <em>Giardia duodenalis</em>, <em>Eimeria</em> ssp., <em>Cryptosporidium baileyi </em>and<em> Cryptosporidium galli</em>.