The WHO newsroom May 2020–states that tobacco epidemic is a gigantic public threat the world has ever faced.Furthermore,greater than 7 million deaths are owed to definitive tobacco usage&1.2 million due to non-smokers being exposed to secondhand smoke or passive smoking[2].Of preventable deaths,caused by use of tobacco,United States of America tops the list.Ironically,there is a steady decrease in estimated number of smokers globally and a rapid increase in number of vapers[3].Nicotine derived from tobacco or nicotiana tabacum is a component of E-cigarettes.Consumption of nicotine in any form has protracted ramifications on one’s health.