Study on the Role of Vitamin D in Systemic Lupus Erythematosus

• 作者: Jiadian Wang Muzi Cui Siyi Wang Xiao Xue Kerong Ren ZhiLu Li Saijia Li Pingping Yan
• 来源期刊: 医学科学进展杂志(英文)
• 学科: 医学
• 关键词: Vitamin D Systemic lupus erythematosus Action research
• 年，卷（期）: 2021,（1）
• 页码范围: 23-28
• 页数: 6页
• 分类号: R73

摘要

Vitamin D is a hormone precursor with multiple biological effects.It binds to vitamin D receptors on target cells.It is an important participant in the metabolism of calcium and phosphorus in vivo.It is closely related to cell cycle,cell proliferation,differentiation,apoptosis,signal transduction and immune regulation.Its role in the treatment of infection,tumor and even immune diseases has been gradually recognized and studied.Patients with systemic lupus erythematosus generally have decreased levels of active vitamin D,and low levels of vitamin D are associated with disease occurrence,disease activity and complications.In the past ten years,a large number of studies have been carried out on it globally to explore the role of vitamin D in the occurrence and development of systemic lupus erythematosus.This paper summarizes its recent research progress.