Osteoclast-derived apoptotic bodies couple bone resorption and formation in bone remodeling

• 来源期刊: 骨研究（英文版）
• 年，卷（期）: 2021,（1）
• 所属期刊栏目: ORIGINAL ARTICLES
• 页码范围: 63-74
• 页数: 12页
• 语种: 英文

摘要

INTRODUCTION Billions of cells undergo apoptosis every day to maintain physiological homeostasis in the human body1. At the late stage of apoptosis, the nucleus and cytoplasm of apoptotic cells are compacted and disassemble into subcellular membrane-bound extracellular vesicles (EVs) named apoptotic bodies (ABs)2–3.