The influence of arterial stiffness in heart failure: a clinical review

• 作者: Mauro Feola
• 来源期刊: 老年心脏病学杂志（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: PERSPECTIVE
• 页码范围: 135-140
• 页数: 6页
• 语种: 英文

摘要

Vascular aging in large arteries plays an important role in contributing to cardiovascular morbidity and mortality.[1]Structural changes include an increase in wall thickness, intima-media thickening ratio is widely attributed to sub-clinical atherosclerosis and it is independently associated with future cardiovascular events.[1] The most marked functional change in large arteries with age consists in a real "stiffening".Arterial stiffness, assessed using pulse wave velocity (PWV), is also a strong independent predictor of cardiovascular events;[1] it plays an important role in terms of age-related increase in systolic blood pressure and pulse pressure,[2] which are both components of blood pressure closely associated with cardiovascular risk in middle-aged or elderly subjects.