Development of Chuanxiong Toothpaste and Establishment of Its Quality Standard

• 作者: Duan Xin Wu Xuemei Wu Yongchao Yang Yu Hu Changjiang
• 来源期刊: 日用化学品科学（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Technologies
• 页码范围: 49-54
• 页数: 6页
• 语种: 英文

摘要

The quality standard of Chuanxiong toothpaste was established. HPLC was used to determine the content of ferulic acid in Chuanxiong toothpaste and TLC was used to identify the Chuanxiong in the toothpaste. The content of active ingredients extracted from Traditional Chinese medicine by decocting water was high, and the corresponding toothpaste had a good hemostatic efect. The identifcation by use of thin layer chromatography (TLC) showed with clear spots and strong specifcity for both the test product and the control product (Levistilide A) as observed under ultraviolet light (254 nm) with n-hexane-ethyl acetate (3:1 ) as the developing agent, which could be used as the basis for the qualitative identifcation of Chuanxiong toothpaste. The ferulic acid in the range of 0.019,3～0.481,7 μg mL-1 showed a good linear relationship with the peak area and the recovery rate of sample was between 99.5％ and 101.2％. This method was simple, stable and reliable, and could be used as the quality control method for ferulic acid in Chuanxiong toothpaste.