The challenge of emerging SARS-CoV-2 mutants to vaccine development

• 作者: Rong Li Jun Liu Hui Zhang
• 来源期刊: 遗传学报
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Commentary
• 页码范围: 102-106
• 页数: 5页
• 语种: 英文

摘要

Since the outbreak of the pandemic,waves of epidemics caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)vari-ants that harbor novel mutations have never paused.Globally,it un-dergoes rapid mutations that involve single-nucleotide polymorphism(SNP)dominantly,whereas ORF1 ab and spike genes contain the most of more than 20,000 mutation sites reported within a year(Fang et al.,2021).