Paraesophageal hernia and iron deficiency anemia:Mechanisms,diagnostics and therapy

• 作者: Christoph G Dietrich Dolores Hübner Joachim W Heise
• 来源期刊: 世界胃肠外科杂志:英文版(电子版)
• 学科: 医学
• 关键词: Iron deficiency anemia Paraesophageal hernia Upside-down stomach Cameron lesions
• 年，卷（期）: 2021,（3）
• 页码范围: 222-230
• 页数: 9页
• 分类号: R57

摘要

There is ample clinical evidence suggesting that the presence of large axial or paraesophageal hernias may lead to iron deficiency anemia.So-called Cameron lesions,as well as other small mucosa erosions,in the sliding area of these diaphragmatic hernias lead to invisible chronic blood loss and consequently to iron depletion.While the spectrum of symptoms in these patients is large,anemia is often not the only indication and typically not the primary indication for surgical correction of diaphragmatic hernias.Drug treatment with proton pump inhibitors and iron substitution can alleviate anemia,but this is not always successful.To exclude other possible bleeding sources in the gastrointestinal tract,a comprehensive diagnostic program is necessary and reviewed in this manuscript.Additionally,we discuss controversies in the surgical management of paraesophageal hernias.