Misalignment is one of the most common faults for the diesel engine.In order to eliminate the misalignment fault of the diesel engine in the process of operation,a targeting self-recovery regula-tion system is constructed by using a movable base and displacement sensors.Misalignment is moni-tored and detected in real time,the value of misalignment is calculated rapidly and accurately,and-intelligent decision is made.Then,the base is moved reversely with a definite target to drive the shaft to translate or rotate,so that the shafts can be recovered to alignment online.A co-simulation model for the self-recovery system is established which consists of a dynamic model of the crankshaft system and control model.The self-recovery regulation process of misalignment is simulated.The simulation results show that the system can accurately calculate the misalignment values,with an er-ror of less than 5 %,and can automatically eliminate the misalignment fault of the diesel engine on-line.The research results provide theoretical support for the self-recovery regulation of misalignment fault,and due to the universality of structure and principle,the self-recovery system is not only suit-able for diesel engine,but also for other rotating machineries.