Effective treatment for COVID-19 remains elusive,though urgently needed in the current pandemic.Repurposing marketed therapies may be an effective strategy for finding treatments quickly and recently,in vitro and clinical testing of such therapies against severe acute respi-ratory syndrome coronavirus 2(SARS-CoV-2)has skyrocketed.However,not all mar-keted drugs showing in vitro efficacy could achieve therapeutic concentrations in humans and discernment of drugs that have favorable pharmacokinetic proper-ties can save time and resources for fu-ture studies.