Effects of soybean raffinose on growth performance,digestibility,humoral immunity and intestinal morphology of growing pigs

• 作者: Zhu Zeng Yalin Zhang Jun He Jie Yu Xiangbing Mao Ping Zheng Yuheng Luo Junqiu Luo Zhiqing Huang Bing Yu Daiwen Chen
• 来源期刊: 动物营养（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: SWINE NUTRITION
• 页码范围: 393-399
• 页数: 7页
• 语种: 英文

摘要

There are appreciable does of raffinose in soybean,but the impacts of raffinose on pigs are poorly investigated.We used 2 experiments to investigate the influence of soybean raffinose on growth per-formance,digestibility,humoral immunity and intestinal morphology of growing pigs.In Exp.1,a total of 30 crossbred (Duroc × Landrace × Yorkshire) barrows (21.93 ± 0.43 kg) were randomly divided into 3 groups,and were fed with the control diet,the control diets supplemented with 0.2％ and 0.5％ raffinose,respectively,for 21 d.Results showed that the addition of 0.2％ or 0.5％ raffinose reduced (P ＜ 0.05)average daily feed intake (ADFI),average daily gain (ADG) and nutrient digestibility,and dietary 0.5％raffinose increased the ratio of feed to gain (P ＜ 0.05).For serum indexes,dietary 0.5％ raffinose decreased growth hormone and increased glucagon-like peptide-2,immunoglobulin G,tumor necrosis factor-α(TNF-α) and interleukin-6 concentration (P ＜ 0.05).In Exp.2,a total of 24 crossbred barrows(38.41 ± 0.45 kg) were randomly divided into 3 groups,and were fed with the control diet (ad libitum),the raffinose diet (0.5％ raffinose,ad libitum),and the control diet in the same amount as the raffinose group (feed-pair group) for 14 d,respectively.Compared with the control diet,dietary 0.5％ raffinose decreased ADFI (P ＜ 0.05).Intriguingly,the raffinose group had lower ADG than the feed-pair group,lower nutrient digestibility,lower amylase activity in duodenum,lower amylase,lipase and trypsin ac-tivities in jejunum and higher TNF-α concentration in serum compared with the other 2 groups,and a higher ratio of villus height to crypt depth compared with the control group (P ＜ 0.05).These results showed that soybean raffinose could reduce feed voluntary intake and body gain while improving in-testinal morphology without a significant negative influence on immunity.Taken together,dietary raffinose could decrease growth performance by reducing both feed intake and nutrient digestibility while inducing humoral immune response of growing pigs.