Predictive model of re-hospitalization in patients with coronary artery disease combined with heart failure

• 作者: CHEN Shu-ling YANG Xu-xi SU Zhi-qi LIU Jin WANG Bo YIN Chang SU Min-ling ZUO Yong-zhen XU You-lan CHEN Hai-fen
• 来源期刊: 岭南心血管病杂志（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: CLINICAL STUDIES
• 页码范围: 248-255
• 页数: 8页
• 语种: 英文

摘要

Background The number of patients with coronary artery disease (CAD) complicated with heart failure (HF)in China is large,the prognosis is poor,and the re-hospitalization rate is high.This study established a predictive model of re-hospitalization factors for patients with CAD and HF.Methods A total of 326 patients with CAD and HF who were hospitalized in the Department of Cardiology of Guangdong Provincial People's Hospital from 2019 to 2020 and were selected.The medical records of patients were collected by electronic medical record sys-tem and followed up for 6 months.Step-wise logistic regression analysis was used to select the potential predic-tors of re-hospitalization.The risk factors related to re-hospitalization of CAD with HF (P＜0.10) were included in the final multivariate logistic regression model.The predictive efficacy of re-hospitalization risk factors for CAD complicated with HF was evaluated by receiver operating characteristic (ROC) curve.Results Re-hospitaliza-tion occurred in 83 patients (26％) during the 6-month follow-up.New York Heart Association (NYHA) class(per 1-1evel increment,adjusted OR:1.45,95％ CI:1.14-2.23,P=0.034),smoking (adjusted OR:2.30,95％ CI:1.20-4.38,P=0.012),drinking (adjusted OR:2.22,95％ CI:1.08-4.56,P=0.029) and the use of statin (adjusted OR:0.50,95％ CI:0.25-0.98) were independent predictors of re-hospitalization.The predictors showed a good performance with the area under curve (AUC) of 0.702 (95％ CI:0.632-0.754).Conclusions This study devel-oped a novel prediction model for re-hospitalization among patients complicated with CAD and HF,which in-cluded four easily accessible clinical variables (NYHA class,smoking,drinking and the use of statins).This mod-el provided a theoretical basis for the identification,intervention and treatment of such patients.