Chinese expert consensus on diagnosis and treatment of trauma-induced hypercoagulopathy

• 作者: Jing-Chun Song Li-Kun Yang Wei Zhao Feng Zhu Gang Wang Yao-Peng Chen Wei-Qin Li Chinese People's Liberation Army Professional Committee of Critical Care Medicine and Chinese Society of Thrombosis,Hemostasis and Critical Care,Chinese Medicine Education Association
• 来源期刊: 军事医学研究（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: POSITION ARTICLE AND GUIDELINES
• 页码范围: 453-467
• 页数: 15页
• 语种: 英文

摘要

Trauma-induced coagulopathy (TIC) is caused by post-traumatic tissue injury and manifests as hypercoagulability that leads to thromboembolism or hypocoagulability that leads to uncontrollable massive hemorrhage.Previous studies on TIC have mainly focused on hemorrhagic coagulopathy caused by the hypocoagulable phenotype of TIC,while recent studies have found that trauma-induced hypercoagulopathy can occur in as many as 22.2％-85.1％ of trauma patients,in whom it can increase the risk of thrombotic events and mortality by 2-to 4-fold.Therefore,the Chinese People's Liberation Army Professional Committee of Critical Care Medicine and the Chinese Society of Thrombosis,Hemostasis and Critical Care,Chinese Medicine Education Association jointly formulated this Chinese Expert Consensus comprising 15 recommendations for the definition,pathophysiological mechanism,assessment,prevention,and treatment of trauma-induced hypercoagulopathy.