基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
In this work, we present a significant step toward in vivo ophthalmic optical coherence tomography and angiography on a photonic integrated chip. The diffraction gratings used in spectral-domain optical coherence tomography can be replaced by photonic integrated circuits comprising an arrayed waveguide grating. Two arrayed waveguide grating designs with 256 channels were tested, which enabled the first chip-based optical coherence tomography and angiography in vivo three-dimensional human retinal measurements. Design 1 supports a bandwidth of 22 nm, with which a sensitivity of up to 91 dB (830μW) and an axial resolution of 10.7μm was measured. Design 2 supports a bandwidth of 48 nm, with which a sensitivity of 90 dB (480μW) and an axial resolution of 6.5μm was measured. The silicon nitride-based integrated optical waveguides were fabricated with a fully CMOS-compatible process, which allows their monolithic co-integration on top of an optoelectronic silicon chip. As a benchmark for chip-based optical coherence tomography, tomograms generated by a commercially available clinical spectral-domain optical coherence tomography system were compared to those acquired with on-chip gratings. The similarities in the tomograms demonstrate the significant clinical potential for further integration of optical coherence tomography on a chip system.
推荐文章
基于0.5chip级LMMSE均衡算法研究
LMMSE
HSPA+
0.5chip级
chip级
Are spatial distributions of major elements in soil influenced by human landscapes?
Major elements
Spatial distribution
Geographical background
Human landscape
Geographic information system
Remote sensing
Groundwater quality assessment using multivariate analysis, geostatistical modeling, and water quali
Groundwater
Multivariate analysis
Geostatistical modeling
Geochemical modeling
Mineralization
Ordinary Kriging
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 Toward optical coherence tomography on a chip: in vivo threedimensional human retinal imaging using photonic integrated circuitbased arrayed waveguide gratings
来源期刊 光:科学与应用(英文版) 学科
关键词
年,卷(期) 2021,(1) 所属期刊栏目 Articles
研究方向 页码范围 71-85
页数 15页 分类号
字数 语种 英文
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (29)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
1988(1)
  • 参考文献(1)
  • 二级参考文献(0)
1991(1)
  • 参考文献(1)
  • 二级参考文献(0)
1998(1)
  • 参考文献(1)
  • 二级参考文献(0)
2000(1)
  • 参考文献(1)
  • 二级参考文献(0)
2002(1)
  • 参考文献(1)
  • 二级参考文献(0)
2003(1)
  • 参考文献(1)
  • 二级参考文献(0)
2006(1)
  • 参考文献(1)
  • 二级参考文献(0)
2008(1)
  • 参考文献(1)
  • 二级参考文献(0)
2011(2)
  • 参考文献(2)
  • 二级参考文献(0)
2012(2)
  • 参考文献(2)
  • 二级参考文献(0)
2013(4)
  • 参考文献(4)
  • 二级参考文献(0)
2015(1)
  • 参考文献(1)
  • 二级参考文献(0)
2016(3)
  • 参考文献(3)
  • 二级参考文献(0)
2017(5)
  • 参考文献(5)
  • 二级参考文献(0)
2018(3)
  • 参考文献(3)
  • 二级参考文献(0)
2020(1)
  • 参考文献(1)
  • 二级参考文献(0)
2021(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
引文网络交叉学科
相关学者/机构
期刊影响力
光:科学与应用(英文版)
双月刊
2095-5545
22-1404/O4
吉林省长春市东南湖大路3888号
eng
出版文献量(篇)
762
总下载数(次)
0
论文1v1指导