Identification of a novel efficient transcriptional activation domain from Chinese fir(Cunninghamia lanceolata)

• 作者: Tengfei Zhu Wenyu Tang Delan Chen Jian Li Jun Su
• 来源期刊: 遗传学报
• 年，卷（期）: 2021,（3）
• 所属期刊栏目: Letter to the Editor
• 页码范围: 257-259
• 页数: 3页
• 语种: 英文

摘要

Direct manipulation of gene expression in vivo is a powerful approach for investigating biological systems and bioengineering in plants(Zhang et al.,2015;Zhao et al.,2015;Lowder et al.,2018).In the past decade,considerable progress has been made in devel-oping techniques for gene targeting.One such technique uses syn-thetic transcriptional activators generated by fusing programmable DNA-binding modules such as zinc-finger domains,transcriptional activator-like(TAL)effectors,clustered regularly interspaced short palindromic repeats(CRISPRs),and CRISPR-associated regulatory systems to a variety of activation domains.These synthetic transcrip-tional activators are used to selectively activate target genes to enhance multiple traits in plants(Liu et al.,2013;Lowder et al.,2018).