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摘要:
Tranexamic acid (TXA) is an anti-fibrinolytic agent which has been proven beneficial in multiple surgical specialties where significant bleeding can occur. Whilst it has been widely available for over 40 years its use within Otorhinolaryngology is still limited. Operations in Otorhinolaryngology are particularly varied with some such as tonsillectomy having the potential for significant life threatening bleeding. Other operations are performed within small confined surgical fields and even small amounts of bleeding can significantly detriment surgical field and increase technical difficulty and operative time. This review evaluated the current literature on the benefits of tranexamic acid within the field of Otorhinolaryngology and Head and Neck Surgery. Overall TXA was demonstrated to be a safe drug with no major adverse effects including thromboembolic events reported in any study. It has been shown to be of particular benefit in rhinology by improving surgical field, reducing operative time and reducing postoperative swelling and ecchymosis. The benefit in tonsillectomy is less clear and further studies are required to evaluate its potential use in the reduction of post tonsillectomy haemorrhage rates.
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篇名 Tranexamic acid in otorhinolaryngology - A contemporary review
来源期刊 世界耳鼻咽喉头颈外科杂志(英文) 学科
关键词 Tranexamic acid Otorhinolaryngology Surgery Bleeding
年,卷(期) 2021,(4) 所属期刊栏目 Review Article
研究方向 页码范围 328-337
页数 10页 分类号
字数 语种 中文
DOI 10.1016/j.wjorl.2020.05.010
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参考文献  (49)
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研究主题发展历程
节点文献
Tranexamic acid
Otorhinolaryngology
Surgery
Bleeding
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
世界耳鼻咽喉头颈外科杂志(英文)
季刊
2095-8811
10-1248/R
北京市西城区宣武门东河沿街69号
eng
出版文献量(篇)
272
总下载数(次)
0
总被引数(次)
110
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