Dear editor,
Dengue is one of the major mosquito-borne diseases and prevalent across tropical and subtropical regions (Carod-Artal et al.2013;Ferguson 2018).Infection with four serotypes of dengue virus (DENV1-4) individually or multiply may cause severe clinical manifestations and complications.In the mainland of China,dengue had been usually characterized as an imported epidemic disease in the past.The first confirmed outbreak of dengue caused by DENV4 occurred in 1978 in Guangdong,a province in south China (Sang et al.2016).Since then,dengue occurred predominantly in south China,and expanded gradually to east and southwest China (Wu et al.2010).Currently,each serotype of DENV circulates and dis-tributes throughout China (Wu et al.2010;Lai et al.2015).