Role of cytokines in the progression of hepatic fibrosis: A review

• 作者: Cong Wu Rong-Zhen Zhang Ting-Shuai Wang Xiao-Bo Zhou Cheng-Yu Ya Xiu-Rong Qin De-Wen Mao
• 来源期刊: 海南医科大学学报（英文版）
• 年，卷（期）: 2021,（13）
• 所属期刊栏目: Review and lectures
• 页码范围: 75-80
• 页数: 6页
• 语种: 英文

摘要

Hepatic fibrosis (HF) is the common pathological basis of all chronic liver diseases, and is a necessary stage for the development of chronic liver disease into cirrhosis. The pathogenesis of liver fibrosis is very complicated. Different cells and cytokines play a major role in the pathogenesis of liver fibrosis. This article focuses on the development mechanism of liver fibrosis, different cells and cytokines (macrophages, natural killer cells, natural killer T cells, tumor necrosis factor, IL-22, transforming growth factor-β, connective tissue growth factor, vascular endothelial growth factor ) Its impact on the development of liver fibrosis is reviewed.