Advances in tracheal reconstruction and tissue engineering

• 作者: Al Haitham Al Shetawi Joanna Weber Mirza Zain Baig Zaid Muslim Faiz Bhora
• 来源期刊: 整形与美容研究（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Review
• 页码范围: 76-86
• 页数: 11页
• 语种: 英文
• DOI: 10.20517/2347-9264.2021.09

摘要

Tracheal stenosis represents a significant challenge. Surgeons continue to search for appropriate reconstructive techniques and grafting materials for long tracheal segment reconstruction. Grafts can be classified as synthetic, allogenic, autogenic, transplant, and engineered. Although none of these grafts have provided overwhelming success, acellular composite engineered grafts have shown early promise and can be applied in benign and malignant tracheal diseases. Intraluminal granulation tissue causing re-stenosis is the biggest challenge in tracheal reconstruction. Tracheal wound healing and tissue regeneration pathways must be deeply explored and better characterized to advance the field of tracheal reconstruction.