The uncontrolled spread of the coro-navirus disease 2019 (COVID-19) pan-demic has led to the emergence of different severe acute respiratory syn-drome coronavirus 2 (SARS-CoV-2) var-iants across the globe.The ongoing global vaccination strategy to curtail the COVID-19 juggernaut is threatened by the rapidly spreading variants of concern(VOC) and other regional mutants,which are less responsive to neutralization by infection-or vaccine-derived antibodies(Gomez et al.,2021;Wang et al.,2021).