Axonal Iron Transport might Contribute to Iron Deposition in Parkinson's Disease

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Research Highlights
• 页码范围: 275-277
• 页数: 3页
• 语种: 英文

摘要

More and more evidence has suggested that iron deposition in the substantia nigra,which is correlated with motor and cognitive dysfunction,is an important trigger factor,potential biomarker,and therapeutic target for Parkinson's disease(PD)[1-3].Although the cellular mechanisms of nigral iron deposition have been well investigated,the exactly mechanisms,especially the origin of the increased nigral iron,have not been fully elucidated.