Peripheral Blood Mitochondrial DNA Copy Number and Hypertension Combined with Albuminuria in Chinese Coal Miners

• 作者: ZHANG Wen Ping ZHANG Yi Fan ZHANG Ying Ying HAN Zhi Chao GAO Yuan Yuan GUO Jian Yong SHI Xiu Jing HU Xiao Qin MU Li Na ZHOU Yun LEI Li Jian
• 来源期刊: 生物医学与环境科学（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 567-571,中插21-中插24
• 页数: 1页
• 语种: 英文
• DOI: 10.3967/bes2021.078

摘要

Hypertension is an increasingly prevalent chronic disease that affects approximately 1 billion people worldwide[1]. Elevated blood pressure inflicts long-term damage to various organs, including the kidneys. Hypertension aggravates the clinical course of chronic kidney disease, and promotes progression toward end-stage renal disease. Among the cases of end-stage renal disease, 30％ are directly attributable to hypertension[2,3]. Though the molecular mechanism responsible for renal injury remains largely unknown, elucidating this mechanism is critical to preventing these deleterious complications.