Apolipoprotein E Drives Early Blood-Brain Barrier Damage in Alzheimer's Disease

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（2）
• 所属期刊栏目: Research Highlights
• 页码范围: 281-283
• 页数: 3页
• 语种: 英文

摘要

Recently,the essential functions of the blood-brain barrier(BBB)have attracted increasing attention in the patho-physiology of Alzheimer's disease(AD)[1].How apolipoprotein E(APOE4),the most important high-risk gene for late-onset AD[2],drives early BBB damage in AD patients remains unclear.Fortunately,Montagne et al.