Effects of Cotrimoxazole Prophylaxis Initiation and Discontinuation on Mortality and Attrition Rates among HIV Patients Who Initiate ART in Southwest China: An Observational Cohort Study

• 作者: ZHU Jin Hui RUAN Yu Hua PAN Stephen YANG Wen Min ZHU Qiu Ying CHEN Huan Huan SHEN Zhi Yong LAN Guang Hua XING Hui SHAO Yi Ming LI Li Ming
• 来源期刊: 生物医学与环境科学（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 646-649,中插13-中插15
• 页数: 1页
• 语种: 英文
• DOI: 10.3967/bes2021.090

摘要

Combination antiretroviral therapy (ART) reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication, enhancing immune recovery, and preventing the onset of opportunistic infections[1].?In?China,?ART?has?rapidly?been?scaled?up since the beginning of the National Free Antiretroviral?Treatment?Program?(NFATP)?in?2003[2]. By the end of 2016, 489,411 individuals diagnosed with?HIV?were?receiving?free?antiretroviral?treatment in China. China is firmly committed to reducing overall AIDS-related mortality and HIV incidence within the country. However, similar to other low-and middle-income countries, the NFATP is challenged by high mortality and attrition shortly after?patients?initiate?ART[3].