CRH Neurons in the Laterodorsal Tegmentum Mediate Acute Stress-induced Anxiety

• 作者: Wenqi Tang Danqing Zhou Siyu Wang Sijia Hao Xiaomeng Wang Mohamed Helmy Junming Zhu Hao Wang
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 999-1004
• 页数: 6页
• 语种: 英文

摘要

Dear Editor, Acute stress-induced anxiety is pervasive in both animals and humans.The natural stress response effectively helps animals to maintain arousal,flee from danger,or simply stay alert to their surroundings.On the other hand,excessive anxiety is strongly associated with many severe psychiatric disorders such as depression,phobia,and posttraumatic stress disorder(PTSD).Although the prob-ability of an individual suffering clinical anxiety reaches an average of 28％during their lifetime,the underlying neural mechanisms of anxiety remain poorly understood.