Effectiveness of Using Mean Corpuscular Volume and Mean Corpuscular Hemoglobin for Beta-thalassemia Carrier Screening in the Guangdong Population of China

• 作者: GU Heng WANG Yong Xia DU Meng Xuan XU Shan Shan ZHOU Bing Yi LI Ming Zhen
• 来源期刊: 生物医学与环境科学（英文版）
• 年，卷（期）: 2021,（8）
• 所属期刊栏目: Letters to the Editor
• 页码范围: 667-671
• 页数: 5页
• 语种: 英文
• DOI: 10.3967/bes2021.094

摘要

Beta (β)-thalassemia is one of the most common hemoglobinopathies worldwide, creating major public health problems and social burdens in many regions. Screening for β-thalassemia carriers is crucial for controlling this condition. To investigate the?effectiveness?of?mean?corpuscular?volume?(MCV) and mean corpuscular hemoglobin (MCH) for screening β-thalassemia, retrospective data were analyzed for 6,779 β-thalassemia carriers subjected to genetic testing following thalassemia screening in Guangdong province between January 2018 and December 2019.