阿尔茨海默病临床前期肠道菌群改变

• 作者: 盛灿 韩璎
• 来源期刊: 中国研究型医院
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: 研究快讯|Research News
• 页码范围: 76
• 页数: 1页
• 语种: 中文
• DOI: 10.19450/j.cnki.jcrh.2021.04.019

摘要

The overall prevalence of dementia in Chinese people aged 60 years and older was 5.30％, imposing a heavy burden on the public and health care systems. Cur-rently, there are no effective therapeutic strategies available to prevent Alzheimer's disease (AD). Accumulating evi-dence implicates that the pathophysiological process of AD begins decades before the emergence of clinical symptoms, and interventions targeting the preclinical AD may offer the best chance for therapeutic success. Subjective cognitive decline (SCD), characterized by a self-report of decline in cognitive function, is considered the earliest symptomatic manifestation of preclinical AD. Therefore, SCD may pro-vide an opportunity for modifying the disease course.