Incidence and Mortality of Acute Disseminated Encephalomyelitis in China:A Nationwide Population-Based Study

• 作者: Yuwen Xiu Hongqiu Gu Xindi Li Zixiao Li Wei-Na Jin Qiang Liu Fu-Dong Shi
• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2021,（6）
• 所属期刊栏目: Letter to the Editor
• 页码范围: 804-808
• 页数: 5页
• 语种: 英文

摘要

Dear Editor, Acute disseminated encephalomyelitis (ADEM) is an immune-mediated demyelinating disorder characterized by a widespread attack of inflammation in the brain and spinal cord that damages myelin[1].ADEM is life-threatening and among the most frequent demyelinating disorders in childhood[2].Its incidence in children has been reported as 0.07-0.51 in Europe[3,4]and 0.2-0.6 in North America[5]per 100,000 children.Apart from Japan,with a reported incidence of 0.4 per 100,000 children[6],data on its incidence are sparse in Asian countries.