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摘要:
Oral inhalation of aerosolized drugs has be widely applied in healing the affected body organs including lesions of the throat and lungs and it is more effiicient than those conventional therapies,such as intravenous drip,intramuscular injection and external topical administration in the aspects of the dosage reduction and side effects of drugs.Never-theless,the traditional atomization devices always exhibit many drawbacks.For example,non-uniformed atomization particle distribution,the instability of transient atomization quantity and difficulties in precise energy control would seriously restrict an extensive use of atomization inhalation therapy.In this study,the principle of intra-hole fluctua-tion phenomenon occurred in the hole is fully explained,and the produced volume change is also estimated.Addi-tionally,the mathematical expression of the atomization rate of the atomizing device is well established.The mecha-nism of the micro-pump is further clarified,and the influence of the vibration characteristics of the atomizing film on the atomization behavior is analyzed theoretically.The curves of sweep frequency against the velocity and amplitude of the piezoelectric vibrator are obtained by the Doppler laser vibrometer,and the corresponding mode shapes of the resonance point are achieved.The influence of vibration characteristics on atomization rate,atomization height and atomization particle size are also verified by experiments,respectively.Both the experimental results and theoretical calculation are expected to provide a guidance for the design of this kind of atomization device in the future.
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篇名 Effects of Vibration Characteristics on the Atomization Performance in the Medical Piezoelectric Atomization Device Induced by Intra-Hole Fluctuation
来源期刊 中国机械工程学报 学科
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年,卷(期) 2021,(6) 所属期刊栏目 Intelligent Manufacturing Technology
研究方向 页码范围 331-339
页数 9页 分类号
字数 语种 英文
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中国机械工程学报
双月刊
1000-9345
11-2737/TH
北京百万庄大街22号期刊部
eng
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2760
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17793
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