Supplementing daidzein in diets improves the reproductive performance,endocrine hormones and antioxidant capacity of multiparous sows

• 作者: Yan Li Guoru He Daiwen Chen Bing Yu Jie Yu Ping Zheng Zhiqing Huang Yuheng Luo Junqiu Luo Xiangbing Mao Hui Yan Jun He
• 来源期刊: 动物营养（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: SWINE NUTRITION
• 页码范围: 1052-1060
• 页数: 9页
• 语种: 英文

摘要

Certain hormones play important roles in modulating mammalian reproductive behaviour.Daidzein is a well-known isoflavonic phytoestrogen that possesses oestrogenic activity.This study was conducted to probe the effects of daidzein supplementation in gestation diets on the reproductive performance in sows.A total of 120 multiparous sows (Landrace × Yorkshire) were randomly assigned to 2 groups(n-60) and fed either a base diet (control) or one containing 200 mg/kg daidzein during gestation.We discovered that daidzein supplementation significantly increased the total number of piglets born per litter and number of piglets born alive per litter (P ＜ 0.05),decreased the farrowing time (P ＜ 0.05) and increased the serum oestrogen and progesterone concentrations (P ＜ 0.05) at 35 d of gestation.More-over,serum immunoglobulin G (IgG) concentration and superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities were higher in the daidzein-treated group than in the control group at 35 d of gestation (P ＜ 0.05).Daidzein increased the serum SOD activity and total anti-oxidative capacity(T-AOC) at 85 d of gestation (P ＜ 0.05).Interestingly,daidzein elevated the expression levels of the sodium-coupled neutral amino acid transporter 1 (SLC38A1) and insulin-like growth factor 1 (IGF-1)genes in the placenta (P ＜ 0.05).These results suggest that daidzein ingestion could improve sow reproductive performance by changing serum hormones,elevating anti-oxidative capacity and up-regulating critical functional genes in the placenta.