A proper excitation wavelength and strong hot-spot effect are of great importance for the application of sur-face-enhanced Raman spectroscopy(SERS)in the field of biochemistry.As a popular SERS substrate,noble metal nanoparticles dimer is analyzed systematically in this paper.The hot-spot effect and the resonance peak position with varying geometric parameters of metal nanoparticles are investigated.Moreover,the excitation wavelength of bimetal-lic structure is discussed as well.The conclusions can provide reference for the selection of metal material at different excitation wavelengths.