Electrochemical Selective Oxidative Synthesis of Diversified Sulfur Heterocycles from β-Ketothioamides

• 作者: Li-Rong Wen Ning-Ning Wang Wu-Bo Du Ming-Zhe Zhu Chao Pan Lin-Bao Zhang Ming Li
• 来源期刊: 中国化学（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: Concise Reports
• 页码范围: 1831-1837
• 页数: 7页
• 语种: 英文
• DOI: 10.1002/cjoc.202100132

摘要

Main observation and conclusion A general and practical protocol for the construction of diversified sulfur heterocycles has been described through organic electro-synthesis means.In undivided cell,dihydrothiophenes,thiazolines and 1,4-dithiines could be easily generated from various available β-ketothioamides under metal-free and external oxidant-free conditions.The transformation underwent smoothly under mild condi-tions and could be easily scaled-up.Moreover,different sulfur heterocycles were generated through varying solvent and 1,4-diaza-bicyclo[2.2.2]octane (DABCO) could enable the hydrogen atom transfer (HAT) process of this transformation.