Visible-light-driven external-photocatalyst-free alkylative carboxylation of alkenes with CO2

• 作者: Ya-Nan Niu Xing-Hao Jin Li-Li Liao He Huang Bo Yu Yu-Ming Yu Da-Gang Yu
• 来源期刊: 中国科学：化学（英文版）
• 年，卷（期）: 2021,（7）
• 所属期刊栏目: ARTICLES
• 页码范围: 1164-1169
• 页数: 6页
• 语种: 英文

摘要

Herein,we report a novel protocol for visible-light-driven alkylative carboxylation of alkenes with CO2 in the absence of external photocatalyst.Under the irradiation of visible light,a variety of 4-alkyl-l,4-dihydropyridines(alkyl-DHPs)serve as not only alkyl radical precursors but also photoexcited reductants probably with the potential to reduce benzyl radicals.Several styrenes and acrylates are applicable in this reaction to give structurally diverse carboxylic acids in good to excellent yields.These reactions feature mild reaction conditions(1 atm of CO2,room temperature,visible light,photocatalyst-and transition metal-free),good functional group tolerance,easy scalability,as well as high regio-,and chemo-selectivity.Mechanistic investigations provide evidence that alkyl radical,benzyl radical and carbanion might be involved in this reaction,providing a novel strategy for CO2 utilization.