As potential cast and wrought Mg alloys,Mg-X (X=Al,Zn,Sn) based alloys have attracted great interest.This work is to develop a dataset of atomic mobilities that is valid over a wide composition range.With the obtained mobilities,and a compatible thermodynamic description,as well as thermophysical parameters,simulations are performed to predict the characteristics of precipitation evolution.Examples are presented for the isothermal aging processes in Mg-x wt.%Al (x =5.9,6,8.8,9),Mg-x wt.%Zn (x =6,6.2,8,8.65),Mg-x wt.%Sn (x =6.04,6.92,8.64) alloys.The simulated size distribution,number density and volume fraction of precipitates reasonably account for the experimental results and provide additional information for further alloy composition design and heat treatment optimization.