A water-soluble β-glucan improves growth performance by altering gut microbiome and health in weaned pigs

• 作者: Yuliang Wu Xue Li Hongnan Liu Yanjun Du Jian Zhou Lijun Zou Xia Xiong Huilin Huang Zhiliang Tan Yulong Yin
• 来源期刊: 动物营养（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: SWINE NUTRITION
• 页码范围: 1345-1351
• 页数: 7页
• 语种: 英文

摘要

Beta-glucan has been shown to have a beneficial effect on gastrointestinal health.This experiment was conducted to investigate the effects of β-glucan isolated from Agrobacterium sp.ZX09 on growth per-formance and intestinal health of weaning pigs.A total of 108 weaned pigs (21 d of age;6.05 ± 0.36 kg)were randomly divided into 3 groups (6 pens/group;6 pigs/pen),and the groups were each treated with the following diets:1) basal diet,2) basal diet supplemented with 20 mg/kg olaquindox,3) basal diet supplemented with 200 mg/kg β-glucan,for 21 d.Compared with the control group,pigs fed with 200 mg/kg β-glucan had greaterBW,average daily gain and duodenal villus height to crypt depth ratio(P ＜ 0.05).Olaquindox increased the duodenal or jejunal villus height of pigs compared with β-glucan.Compared with the control group,β-glucan tended to increase the occludin mRNA expression in the jejunum (0.05 ＜ P ＜ 0.10).Beta-glucan enriched the beneficial microbiota in the ileum of pigs (P ＜ 0.05).In conclusion,β-glucan may promote growth performance by improving intestinal health and increasing beneficial microbiota of weaned pigs.The study results will provide valuable theoretical guidance for the utilization of β-glucan in weaned pigs.