Microstructure, fracture behavior, in vitro corrosion resistance,and cytotoxicity of Zn-Mg/Mg-Zn-HAp laminated composites produced by spark plasma sintering

• 作者: Ya-Kai Zhang Ze-Qin Cui Dian-Qing Gong Wen-Xian Wang Wei-Li Cheng
• 来源期刊: 稀有金属（英文版）
• 年，卷（期）: 2021,（4）
• 所属期刊栏目: ORIGINAL ARTICLES
• 页码范围: 939-951
• 页数: 13页
• 语种: 英文

摘要

Ideal biodegradable materials exhibit suitable degradation rates and sufficient mechanical properties for their specific application.With these parameters in mind,Zn-Mg/Mg-Zn-hydroxyapatite (HAp) laminated composites were designed and fabricated by spark plasma sintering.This paper describes the structure,mechanical properties,in vitro corrosion resistance,and cytotoxicity of the Zn-Mg/Mg-Zn-HAp laminated composites.The compressive strength and elastic moduli of the laminated composites matched that of cortical bone and could effectively reduce the stress shielding effect as an implant with good biomechanical compatibility.Analysis of the fracture path and morphology after fracture toughness tests indicated that the Zn-Mg/Mg-Zn-HAp laminated composites exhibited significant capacity to prevent crack propagation,improving the fracture toughness.In vitro degradation experiments showed that the design of the laminated structure can provide a gradient degradation rate for the material.Furthermore,the laminated composites exhibited excellent biocompatibility and are promising candidates for orthopedic implants,