Novel Non-Protein Biomarkers for Early Detection of Hepatocellular Carcinoma

• 作者: Ghassan K.Abou-Alfa Lin Wu Augusto Villanueva
• 来源期刊: 工程（英文）
• 年，卷（期）: 2021,（10）
• 所属期刊栏目: New Technology of Tumor Diagnosis and Treatment-Review
• 页码范围: 1369-1374
• 页数: 6页
• 语种: 英文

摘要

Early detection of hepatocellular carcinoma(HCC)while in its early stages is critical for reducing HCC mortality in high-risk patients.However,highly sensitive and specific surveillance biomarkers for early-stage HCC detection are still lacking.In recent years,great efforts have been made to research tumor-derived molecular features that are detectable in circulation,such as circulating tumor deoxyri-bonucleic acid and circulating tumor ribonucleic acid,in order to explore their potential as non-invasive biomarker candidates in many tumor types.In this review,we summarize current studies on these new approaches and their application in early HCC detection.